Abl1 11350

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Gene ID: 11350
Gene symbol: abl1
Gene Description: c-abl oncogene 1, receptor tyrosine kinase
Aliases: Abl; AI325092; c-Abl; E430008G22Rik; MGC117749
Human Ortholog Gene ID:
Reviewer Judgement: Indeterminate - There is no evidence for or against this gene's role as a TF
Functional Classification:

Evidence:

Pubmed ID Function Species Evidence Strength Reviewer's Comments Reviewer
[16091742] Transactivation Human; Mouse Weak Activated Abl shown to be involved in transactivation of EGR1 promoter-luc. Promoter deletion constructs show the -480/-235 important. Human 293, U20S inducible lines and murine embryonic fibroblasts used. Warren Cheung
Additional Reviewer Comments:
Reviewer: Warren Cheung

Part of the family of non-receptor tyrosine kinases. No direct TF activity observed, but it is sufficient to activate the EGR1 promoter.


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Facts about Abl1 11350RDF feed
Gene description c-abl oncogene 1, receptor tyrosine kinase  +
Gene id 11,350  +
Gene judgment Indeterminate - There is no evidence for or against this gene's role as a TF  +
Gene symbol abl1  +, Abl  +, AI325092  +, c-Abl  +, E430008G22Rik  +, and MGC117749  +
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