Cdk9 107951

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Gene ID: 107951
Gene symbol: cdk9
Gene Description: cyclin-dependent kinase 9 (cdc2-related kinase)
Aliases: PITALRE
Human Ortholog Gene ID: [1025]
Reviewer Judgement: TF Gene
Functional Classification: Transcription Factor Binding: tf co-factor binding;

Basal Transcription Factor

Homolog Cluster(s): 107951

Evidence:

Pubmed ID Function Species Evidence Strength Reviewer's Comments Reviewer
[10656684] TF PPI Human Medium Interaction with myb-1 indicates that CDK9 has some TF like characteristics

Paper indicates dominant negative CDK9 can suppress transcription of Cmyb and the opposite (more CDK9 increases transcription

Wyeth Wasserman
[12063565] Other Human Weak review article linking CDK9 and transcription Wyeth Wasserman
Additional Reviewer Comments:
Reviewer: Wyeth Wasserman

aka PITALRE interactions with pol II and phosphorylates it also appears to interact with and phosphorylate other TFs "the catalytic subunit of the positive-transcription elongation factor b"


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Facts about Cdk9 107951RDF feed
Gene description cyclin-dependent kinase 9 (cdc2-related kinase)  +
Gene id 107,951  +
Gene judgment TF Gene  +
Gene symbol cdk9  +, and PITALRE  +
Gene taxonomy Transcription Factor Binding: tf co-factor binding  +, and Basal Transcription Factor  +
Homolog cluster 107,951  +
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