Cited2 17684

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Gene ID: 17684
Gene symbol: cited2
Gene Description: cbp/p300-interacting transactivator, with glu/asp-rich carboxy-terminal domain, 2
Aliases: AI835299; ER154-like; Mrg1; Msg2; p35srj
Human Ortholog Gene ID: [10370]
Reviewer Judgement: TF Gene
Functional Classification: Transcription Factor Binding: tf co-factor binding
Homolog Cluster(s): 12705

Evidence:

Pubmed ID Function Species Evidence Strength Reviewer's Comments Reviewer
[9434189] Co-activation; Transactivation; TF PPI Human Weak co-activation but no DNA binding Wyeth Wasserman
[11044621] Co-activation; Transactivation; TF PPI Human; Mouse Weak interactions with CBP; co-activating function Wyeth Wasserman
[12778114] Co-activation; Transactivation; TF PPI Human Strong CITED2 competes for cysteine-histidine-rich 1 (CH1) domain of p300/CBP by binding CH1 with high affinity Wyeth Wasserman
Additional Reviewer Comments:
Reviewer: Wyeth Wasserman

A protein which physically interacts with CBP to suppress interactions with TFs. No DNA binding, but clearly a TF.


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Facts about Cited2 17684RDF feed
Gene description cbp/p300-interacting transactivator, with glu/asp-rich carboxy-terminal domain, 2  +
Gene id 17,684  +
Gene judgment TF Gene  +
Gene symbol cited2  +, AI835299  +, ER154-like  +, Mrg1  +, Msg2  +, and p35srj  +
Gene taxonomy Transcription Factor Binding: tf co-factor binding  +
Homolog cluster 12,705  +
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