Daxx 13163

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Gene ID: 13163
Gene symbol: daxx
Gene Description: fas death domain-associated protein
Aliases: MGC150289
Human Ortholog Gene ID: [1616]
Reviewer Judgement: TF Gene
Functional Classification: Transcription Factor Binding: tf co-factor binding
Homolog Cluster(s): 13163


Pubmed ID Function Species Evidence Strength Reviewer's Comments Reviewer
[11799127] Co-activation Mouse Strong Upon transient transfection assay of Daxx in B cells expressing endogenous Daxx and Pax5, not only transcriptional corepression is observed but also, unexpectedly, coactivation in M12.4.1 and A20 mouse B cell lines. David Martin
[12529400] Other Mouse Strong Daxx acts as a transcriptional repressor when phosphorylated by HIPK1 on Ser 669. Daxx activity is measured in an overexpression context, by observing the level of expression of reporter genes fused with luciferase. David Martin
Additional Reviewer Comments:
Reviewer: David Martin

In summary, Daxx acts as a: transcription coactivator transcription corepressor transcriptional repressor

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Facts about Daxx 13163RDF feed
Gene description fas death domain-associated protein  +
Gene id 13,163  +
Gene judgment TF Gene  +
Gene symbol daxx  +, and MGC150289  +
Gene taxonomy Transcription Factor Binding: tf co-factor binding  +
Homolog cluster 13,163  +
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