Ddx3x 13205

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Gene ID: 13205
Gene symbol: ddx3x
Gene Description: dead/h (asp-glu-ala-asp/his) box polypeptide 3, x-linked
Aliases: D1Pas1-rs2; Ddx3; Fin14
Human Ortholog Gene ID: [1654]
Reviewer Judgement: TF Gene
Functional Classification: Transcription Factor Binding: tf co-factor binding
Homolog Cluster(s): 13205

Evidence:

Pubmed ID Function Species Evidence Strength Reviewer's Comments Reviewer
[16818630] TF PPI Human Strong Endogenous DDX3 is pulled down by GST-Sp1 but not by GST control beads, suggesting a specific interaction between DDX3 and Sp1 in vitro. Transiently expressed FLAG-Sp1 and endogenous DDX3 were coimmunoprecipitated by anti-FLAG antibody in HuH-7 cells. Amy Ticoll
Additional Reviewer Comments:
Reviewer: Amy Ticoll

Endogenous DDX3 is pulled down by GST-Sp1. Transiently expressed FLAG-Sp1 and endogenous DDX3 were coimmunoprecipitated by anti-FLAG antibody. Co-transfection assays indicate DDX3 cooperates with Sp1 to up-regulate the promoter activity of p21(waf1/cip1).


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Facts about Ddx3x 13205RDF feed
Gene description dead/h (asp-glu-ala-asp/his) box polypeptide 3, x-linked  +
Gene id 13,205  +
Gene judgment TF Gene  +
Gene symbol ddx3x  +, D1Pas1-rs2  +, Ddx3  +, and Fin14  +
Gene taxonomy Transcription Factor Binding: tf co-factor binding  +
Homolog cluster 13,205  +
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