Dlx3 13393

From TFCatWiki

Jump to: navigation, search

External Links

Gene ID: 13393
Gene symbol: dlx3
Gene Description: distal-less homeobox 3
Aliases: AV237891; Dlx-3
Human Ortholog Gene ID: [1747]
Reviewer Judgement: TF Gene
Functional Classification: DNA-Binding: sequence-specific
DBD Protein Group Classification: Helix-Turn-Helix Group
DBD Protein Group/Family Classification: Helix-Turn-Helix Group / Homeodomain Family
Homolog Cluster(s): 103889; 104360

Evidence:

Pubmed ID Function Species Evidence Strength Reviewer's Comments Reviewer
[16687405] DNA Binding; TF PPI Human Medium EMSA studies using nuclear extracts and antiserum against Dlx3 indicates endogenous Dlx3 can bind to a specific site in the Esx1 gene promoter. Amy Ticoll
Additional Reviewer Comments:
Reviewer: Amy Ticoll

EMSA studies indicate Dlx3 can bind to a specific site in the Esx1 gene promoter. Dlx3 overexpression increases Esx1 luciferase activity in transfection assays (JEG3 cells).


DISCUSSION PAGE link for this gene

VIEW gene annotation feedback in the [TFCat Annotation Feedback Reports Inquiry]

REPORT gene annotation feedback on the [TFCat Annotation Feedback Reporting System] Help is available here


The section below defines information for semantic searching. Please see the help page for more information on this section.

Facts about Dlx3 13393RDF feed
Gene description distal-less homeobox 3  +
Gene id 13,393  +
Gene judgment TF Gene  +
Gene symbol dlx3  +, AV237891  +, and Dlx-3  +
Gene taxonomy DNA-Binding: sequence-specific  +
Homolog cluster 103,889  +, and 104,360  +
Protein family 1.1 Helix-Turn-Helix Group/2 Homeodomain Family  +
Protein group 1.1 Helix-Turn-Helix Group   +
Personal tools