Ebf1 13591

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Gene ID: 13591
Gene symbol: ebf1
Gene Description: early b-cell factor 1
Aliases: 9830166E18Rik; AW990631; Ebf; O/E-1; Olf-1; Olf1
Human Ortholog Gene ID: [1879]
Reviewer Judgement: TF Gene Candidate
Functional Classification: DNA-Binding: non-sequence-specific
DBD Protein Group Classification: Zipper-Type Group
DBD Protein Group/Family Classification: Zipper-Type Group / Helix-Loop-Helix Family
Homolog Cluster(s): 13591

Evidence:

Pubmed ID Function Species Evidence Strength Reviewer's Comments Reviewer
[12446773] Non-specific DNA Mouse Strong In vivo DNAse footprinting in 10^7 cells indicates EBF binds the mb-1 promoter. EMSAs with performed with nuclear extracts confirm the interaction. Amy Ticoll
Additional Reviewer Comments:
Reviewer: Amy Ticoll

EMSA and in vivo DNAse footprinting experiments indicate EBF binds the mb-1 promoter. Microarray analysis indicates expression of endogenous mb-1 transcripts correlates most closely with EBF expression.


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Facts about Ebf1 13591RDF feed
Gene description early b-cell factor 1  +
Gene id 13,591  +
Gene judgment TF Gene Candidate  +
Gene symbol ebf1  +, 9830166E18Rik  +, AW990631  +, Ebf  +, O/E-1  +, Olf-1  +, and Olf1  +
Gene taxonomy DNA-Binding: non-sequence-specific  +
Homolog cluster 13,591  +
Protein family 3 Zipper-Type Group/22 Helix-Loop-Helix Family  +
Protein group 3 Zipper-Type Group   +
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