Egr3 13655

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Gene ID: 13655
Gene symbol: egr3
Gene Description: early growth response 3
Aliases: MGC124006; MGC124009; Pilot
Human Ortholog Gene ID: [1960]
Reviewer Judgement: TF Gene Candidate
Functional Classification: DNA-Binding: sequence-specific
DBD Protein Group Classification: Zinc-coordinating Group
DBD Protein Group/Family Classification: Zinc-coordinating Group / BetaBetaAlpha-zinc finger Family
Homolog Cluster(s): 107586

Evidence:

Pubmed ID Function Species Evidence Strength Reviewer's Comments Reviewer
[1906159] Transactivation Mouse Medium EGR3 transactivates a CAT construct containing the Egr-1 binding site. Induction is 16-fold compared to the negative control without the binding site. Amy Ticoll
Additional Reviewer Comments:
Reviewer: Amy Ticoll

EGR3 significantly transactivates a CAT construct containing the Egr-1 binding site. No experiments found confirming the DNA-binding specificity of EGR3.


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Facts about Egr3 13655RDF feed
Gene description early growth response 3  +
Gene id 13,655  +
Gene judgment TF Gene Candidate  +
Gene symbol egr3  +, MGC124006  +, MGC124009  +, and Pilot  +
Gene taxonomy DNA-Binding: sequence-specific  +
Homolog cluster 107,586  +
Protein family 2.1 Zinc-coordinating Group/17 BetaBetaAlpha-zinc finger Family  +
Protein group 2.1 Zinc-coordinating Group   +
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