Elf1 13709

From TFCatWiki

Jump to: navigation, search

External Links

Gene ID: 13709
Gene symbol: elf1
Gene Description: e74-like factor 1
Aliases: Elf-1; mElf-1; p70; Sts1
Human Ortholog Gene ID: [1997]
Reviewer Judgement: TF Gene
Functional Classification: DNA-Binding: sequence-specific
DBD Protein Group Classification: Winged Helix-Turn-Helix
DBD Protein Group/Family Classification: Winged Helix-Turn-Helix / Ets Domain Family
Homolog Cluster(s): 104156


Pubmed ID Function Species Evidence Strength Reviewer's Comments Reviewer
[12065417] DNA Binding; TF PPI Mouse Strong E74-like factor 1 binds to a SCL stem cell enhancer (EMSA, chIP).

It forms an enhanceosome with GATA-2 and Fli-1 on this enhancer as shown by the EMSA and GST pull-down experiments.

Elodie Portales-Casamar
[16002702] DNA Binding Mouse Strong Gel shift assays and chromatin immunoprecipitation experiments showed that E74-like factor 1 binds to the CD1D1 promoter. Elodie Portales-Casamar
Additional Reviewer Comments:
Reviewer: Elodie Portales-Casamar

specific DNA binding is shown with multiple experiment in different genes for this factor. No direct transactivation is shown.

DISCUSSION PAGE link for this gene

VIEW gene annotation feedback in the [TFCat Annotation Feedback Reports Inquiry]

REPORT gene annotation feedback on the [TFCat Annotation Feedback Reporting System] Help is available here

The section below defines information for semantic searching. Please see the help page for more information on this section.

Facts about Elf1 13709RDF feed
Gene description e74-like factor 1  +
Gene id 13,709  +
Gene judgment TF Gene  +
Gene symbol elf1  +, Elf-1  +, mElf-1  +, p70  +, and Sts1  +
Gene taxonomy DNA-Binding: sequence-specific  +
Homolog cluster 104,156  +
Protein family 1.2 Winged Helix-Turn-Helix/16 Ets Domain Family  +
Protein group 1.2 Winged Helix-Turn-Helix   +
Personal tools