Elf2 69257

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Gene ID: 69257
Gene symbol: elf2
Gene Description: e74-like factor 2
Aliases: 2610036A20Rik; A230104O07Rik; AW111824; BB183398; EU32; MGC102660; NERF; NERF-1A; NERF-1B; NERF-2
Human Ortholog Gene ID: [1998]
Reviewer Judgement: TF Gene
Functional Classification: DNA-Binding: sequence-specific
DBD Protein Group Classification: Winged Helix-Turn-Helix
DBD Protein Group/Family Classification: Winged Helix-Turn-Helix / Ets Domain Family
Homolog Cluster(s): 104156

Evidence:

Pubmed ID Function Species Evidence Strength Reviewer's Comments Reviewer
[8756667] DNA Binding; Transactivation Human Strong ELF2 (NERF2) synthesized in reticulocyte lysates binds to the lyn promoter Ets site in gel shift assays.

ELF2 activates a reporter construct containing two copies of the lyn or blk promoter Ets sites following transient transfection in HeLa cells.

Rob Sladek
Additional Reviewer Comments:
Reviewer: Rob Sladek

ELF2 (NERF2) synthesized in reticulocyte lysates binds to the lyn promoter Ets site in gel shift assays. ELF2 activates a reporter construct containing two copies of the lyn or blk promoter Ets sites following transient transfection in HeLa cells.


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Facts about Elf2 69257RDF feed
Gene description e74-like factor 2  +
Gene id 69,257  +
Gene judgment TF Gene  +
Gene symbol elf2  +, 2610036A20Rik  +, A230104O07Rik  +, AW111824  +, BB183398  +, EU32  +, MGC102660  +, NERF  +, NERF-1A  +, NERF-1B  +, and NERF-2  +
Gene taxonomy DNA-Binding: sequence-specific  +
Homolog cluster 104,156  +
Protein family 1.2 Winged Helix-Turn-Helix/16 Ets Domain Family  +
Protein group 1.2 Winged Helix-Turn-Helix   +
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