Elk3 13713

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Gene ID: 13713
Gene symbol: elk3
Gene Description: elk3, member of ets oncogene family
Aliases: D430049E23Rik; Erp; Etrp; Net; Sap-2
Human Ortholog Gene ID: [2004]
Reviewer Judgement: TF Gene
Functional Classification: DNA-Binding: sequence-specific
DBD Protein Group Classification: Winged Helix-Turn-Helix
DBD Protein Group/Family Classification: Winged Helix-Turn-Helix / Ets Domain Family
Homolog Cluster(s): 104156

Evidence:

Pubmed ID Function Species Evidence Strength Reviewer's Comments Reviewer
[7958835] DNA Binding Mouse Medium In vitro translated Net (Elk3) binds specifically to the ets motifs in EMSA. Amy Ticoll
[12896968] Transactivation Mouse Medium represses expression Amy Ticoll
Additional Reviewer Comments:
Reviewer: Amy Ticoll

In vitro translated Net (Elk3) binds specifically to ets motifs in EMSA. It is reported that Net expression in NIH-3T3 cells represses transcription through ets motifs.


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Facts about Elk3 13713RDF feed
Gene description elk3, member of ets oncogene family  +
Gene id 13,713  +
Gene judgment TF Gene  +
Gene symbol elk3  +, D430049E23Rik  +, Erp  +, Etrp  +, Net  +, and Sap-2  +
Gene taxonomy DNA-Binding: sequence-specific  +
Homolog cluster 104,156  +
Protein family 1.2 Winged Helix-Turn-Helix/16 Ets Domain Family  +
Protein group 1.2 Winged Helix-Turn-Helix   +
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