Emx2 13797

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Gene ID: 13797
Gene symbol: emx2
Gene Description: empty spiracles homolog 2 (drosophila)
Aliases: Pdo
Human Ortholog Gene ID: [2018]
Reviewer Judgement: TF Gene Candidate
Functional Classification: DNA-Binding: sequence-specific
DBD Protein Group Classification: Helix-Turn-Helix Group
DBD Protein Group/Family Classification: Helix-Turn-Helix Group / Homeodomain Family
Homolog Cluster(s): 103889

Evidence:

Pubmed ID Function Species Evidence Strength Reviewer's Comments Reviewer
[1352754] DNA Binding Other Strong Homeodomain with developmental pattern of expression is essentially certain to be a TF Jared Roach
[16919471] Transactivation Mouse Weak Transcript profiling with Emx2-/- mice. " These findings identify potential targets of EMX2 that might account for its function and the defects in Emx2-/- cortex, and suggest that the Odz family of transmembrane proteins influences cortical area patterning downstream to EMX2 and PAX6."

"Using secondary screening by in situ hybridization, we selected five genes for further analysis, Cdk4, Cofilin1, Crmp1, ME2, and Odz4,"

Jared Roach
Additional Reviewer Comments:


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Facts about Emx2 13797RDF feed
Gene description empty spiracles homolog 2 (drosophila)  +
Gene id 13,797  +
Gene judgment TF Gene Candidate  +
Gene symbol emx2  +, and Pdo  +
Gene taxonomy DNA-Binding: sequence-specific  +
Homolog cluster 103,889  +
Protein family 1.1 Helix-Turn-Helix Group/2 Homeodomain Family  +
Protein group 1.1 Helix-Turn-Helix Group   +
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