Erf 13875

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Gene ID: 13875
Gene symbol: erf
Gene Description: ets2 repressor factor
Aliases:
Human Ortholog Gene ID: [2077]
Reviewer Judgement: TF Gene
Functional Classification: DNA-Binding: sequence-specific
DBD Protein Group Classification: Winged Helix-Turn-Helix
DBD Protein Group/Family Classification: Winged Helix-Turn-Helix / Ets Domain Family
Homolog Cluster(s): 104156

Evidence:

Pubmed ID Function Species Evidence Strength Reviewer's Comments Reviewer
[12533699] DNA Binding Human Medium ERF binds the 21 bp repeats of the MIEP ets consensus site in EMSA analysis. Binding is abolished in the presence of specific cold competitor, but not by a similar concentration of the non-specific competitor. Experiments conducted with appropriate controls. Amy Ticoll
Additional Reviewer Comments:
Reviewer: Amy Ticoll

ERF specifically binds the 21 bp repeats of the MIEP ets consensus site in EMSA analysis. ERF represses transcription from the MIEP in transient transfection assays in undifferentiated T2 cells.


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Facts about Erf 13875RDF feed
Gene description ets2 repressor factor  +
Gene id 13,875  +
Gene judgment TF Gene  +
Gene symbol erf  +
Gene taxonomy DNA-Binding: sequence-specific  +
Homolog cluster 104,156  +
Protein family 1.2 Winged Helix-Turn-Helix/16 Ets Domain Family  +
Protein group 1.2 Winged Helix-Turn-Helix   +
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