Esrra 26379

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Gene ID: 26379
Gene symbol: esrra
Gene Description: estrogen related receptor, alpha
Aliases: Err1; ERRalpha; Estrra; Nr3b1
Human Ortholog Gene ID: [2101]
Reviewer Judgement: TF Gene
Functional Classification: DNA-Binding: sequence-specific
DBD Protein Group Classification: Zinc-coordinating Group
DBD Protein Group/Family Classification: Zinc-coordinating Group / Hormone-nuclear Receptor Family
Homolog Cluster(s): 110784

Evidence:

Pubmed ID Function Species Evidence Strength Reviewer's Comments Reviewer
[9271417] DNA Binding; Transactivation Mouse Strong DNA binding was demonstrated using a PCR-based site-selection strategy. EMSA assays also show that Esrra binds to the MCAD promoter. Transactivation was shown by transient transfection using MCAD-luciferase reporter and VP16-Esrra constructs. Sarav Sundararajan
Additional Reviewer Comments:


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Facts about Esrra 26379RDF feed
Gene description estrogen related receptor, alpha  +
Gene id 26,379  +
Gene judgment TF Gene  +
Gene symbol esrra  +, Err1  +, ERRalpha  +, Estrra  +, and Nr3b1  +
Gene taxonomy DNA-Binding: sequence-specific  +
Homolog cluster 110,784  +
Protein family 2.1 Zinc-coordinating Group/18 Hormone-nuclear Receptor Family  +
Protein group 2.1 Zinc-coordinating Group   +
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