Fev 260298

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Gene ID: 260298
Gene symbol: fev
Gene Description: fev (ets oncogene family)
Aliases: mPet-1; Pet-1; Pet1
Human Ortholog Gene ID: [54738]
Reviewer Judgement: TF Gene
Functional Classification: DNA-Binding: sequence-specific
DBD Protein Group Classification: Winged Helix-Turn-Helix
DBD Protein Group/Family Classification: Winged Helix-Turn-Helix / Ets Domain Family
Homolog Cluster(s): 104156

Evidence:

Pubmed ID Function Species Evidence Strength Reviewer's Comments Reviewer
[9468386] DNA Binding; Transactivation Rat Strong This paper describes the cloning of Pet-1. EMSA studies using an oligonucleotide

bearing a single PEA3 ETS DNA-binding motif show that Pet-1 can bind to this sequence. Luciferase reporter assays show that Pet-1 can repress transcription of the Beta 43' enhancer sequence.

Sarav Sundararajan
Additional Reviewer Comments:


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Facts about Fev 260298RDF feed
Gene description fev (ets oncogene family)  +
Gene id 260,298  +
Gene judgment TF Gene  +
Gene symbol fev  +, mPet-1  +, Pet-1  +, and Pet1  +
Gene taxonomy DNA-Binding: sequence-specific  +
Homolog cluster 104,156  +
Protein family 1.2 Winged Helix-Turn-Helix/16 Ets Domain Family  +
Protein group 1.2 Winged Helix-Turn-Helix   +
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