Foxf2 14238

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Gene ID: 14238
Gene symbol: foxf2
Gene Description: forkhead box f2
Aliases: Fkh20; FREAC2; LUN
Human Ortholog Gene ID: [2295]
Reviewer Judgement: TF Gene
Functional Classification: DNA-Binding: sequence-specific
DBD Protein Group Classification: Winged Helix-Turn-Helix
DBD Protein Group/Family Classification: Winged Helix-Turn-Helix / Forkhead Domain Family
Homolog Cluster(s): 108655

Evidence:

Pubmed ID Function Species Evidence Strength Reviewer's Comments Reviewer
[8626802] DNA Binding Human Strong In a gel shift assay with a FREAC probe and extracts from COS-7 cells, FREAC2 (Foxf2) binds to the probe. DNaseI footprinting verifies that FREAC2 protein binds to predicted sites in the SPB promoter. Amy Ticoll
Additional Reviewer Comments:
Reviewer: Amy Ticoll

In a gel shift assay with a FREAC probe and cell extracts, FREAC2 (Foxf2) binds to the probe. DNaseI footprinting verifies that FREAC2 protein binds to predicted sites in the SPB promoter. The SPB promoter construct could be transactivated by FREAC2 in C11 cells.


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Facts about Foxf2 14238RDF feed
Gene description forkhead box f2  +
Gene id 14,238  +
Gene judgment TF Gene  +
Gene symbol foxf2  +, Fkh20  +, FREAC2  +, and LUN  +
Gene taxonomy DNA-Binding: sequence-specific  +
Homolog cluster 108,655  +
Protein family 1.2 Winged Helix-Turn-Helix/102 Forkhead Domain Family  +
Protein group 1.2 Winged Helix-Turn-Helix   +
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