Foxi1 14233

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Gene ID: 14233
Gene symbol: foxi1
Gene Description: forkhead box i1
Aliases: 5830401E05Rik; Fkh10; FREAC6; HFH-3; Hfh3
Human Ortholog Gene ID: [2299]
Reviewer Judgement: TF Gene
Functional Classification: DNA-Binding: sequence-specific
DBD Protein Group Classification: Winged Helix-Turn-Helix
DBD Protein Group/Family Classification: Winged Helix-Turn-Helix / Forkhead Domain Family
Homolog Cluster(s): 108655

Evidence:

Pubmed ID Function Species Evidence Strength Reviewer's Comments Reviewer
[9153225] DNA Binding; Transactivation Human; Mouse Strong DNA binding sites have been determined by EMSA.

Transcriptional activation : Cotransfection assay consisted of a reporter plasmid containing four copies of the high affinity HFH-3 binding site cloned upstream of a TATA box-driven chloramphenicol acetyltransferase (CAT) gene and a CMV promoter-driven beta -galactosidase control plasmid to normalize for differences in transfection efficiency.

David Martin
Additional Reviewer Comments:


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Facts about Foxi1 14233RDF feed
Gene description forkhead box i1  +
Gene id 14,233  +
Gene judgment TF Gene  +
Gene symbol foxi1  +, 5830401E05Rik  +, Fkh10  +, FREAC6  +, HFH-3  +, and Hfh3  +
Gene taxonomy DNA-Binding: sequence-specific  +
Homolog cluster 108,655  +
Protein family 1.2 Winged Helix-Turn-Helix/102 Forkhead Domain Family  +
Protein group 1.2 Winged Helix-Turn-Helix   +
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