Foxo1 56458

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Gene ID: 56458
Gene symbol: foxo1
Gene Description: forkhead box o1
Aliases: Afxh; AI876417; FKHR; Fkhr1; Foxo1a
Human Ortholog Gene ID: [2308]
Reviewer Judgement: TF Gene
Functional Classification: DNA-Binding: sequence-specific
DBD Protein Group Classification: Winged Helix-Turn-Helix
DBD Protein Group/Family Classification: Winged Helix-Turn-Helix / Forkhead Domain Family
Homolog Cluster(s): 108655

Evidence:

Pubmed ID Function Species Evidence Strength Reviewer's Comments Reviewer
[10385407] DNA Binding; Transactivation Human Strong EMSA assays using a GST-fusion of FKHR show that FKHR binds to the IGFBP-1 insulin response element. CAT reporter assays using the IGFBP-1 promoter demonstrate transactivation activity. Sarav Sundararajan
Additional Reviewer Comments:


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Facts about Foxo1 56458RDF feed
Gene description forkhead box o1  +
Gene id 56,458  +
Gene judgment TF Gene  +
Gene symbol foxo1  +, Afxh  +, AI876417  +, FKHR  +, Fkhr1  +, and Foxo1a  +
Gene taxonomy DNA-Binding: sequence-specific  +
Homolog cluster 108,655  +
Protein family 1.2 Winged Helix-Turn-Helix/102 Forkhead Domain Family  +
Protein group 1.2 Winged Helix-Turn-Helix   +
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