Foxp3 20371

From TFCatWiki

Jump to: navigation, search

External Links

Gene ID: 20371
Gene symbol: foxp3
Gene Description: forkhead box p3
Aliases: JM2; scurfin; sf
Human Ortholog Gene ID: [50943]
Reviewer Judgement: TF Gene
Functional Classification: DNA-Binding: sequence-specific
DBD Protein Group Classification: Winged Helix-Turn-Helix
DBD Protein Group/Family Classification: Winged Helix-Turn-Helix / Forkhead Domain Family
Homolog Cluster(s): 108655

Evidence:

Pubmed ID Function Species Evidence Strength Reviewer's Comments Reviewer
[17028180] DNA Binding Human; Mouse Medium ChIP assay with extracts from 1-2 x 10^6 cells indicates Foxp3 binds specific sites within the upstream regions of the IL-2 and IFN{gamma} genes. Amy Ticoll
Additional Reviewer Comments:
Reviewer: Amy Ticoll

ChIP assay indicates Foxp3 binds specific sites within the upstream regions of the IL-2 and IFN{gamma} genes. Transfection experiments show Foxp3 modifies transcription regulation of these genes by modulating histone acetylation/deacetylation.


DISCUSSION PAGE link for this gene

VIEW gene annotation feedback in the [TFCat Annotation Feedback Reports Inquiry]

REPORT gene annotation feedback on the [TFCat Annotation Feedback Reporting System] Help is available here


The section below defines information for semantic searching. Please see the help page for more information on this section.

Facts about Foxp3 20371RDF feed
Gene description forkhead box p3  +
Gene id 20,371  +
Gene judgment TF Gene  +
Gene symbol foxp3  +, JM2  +, scurfin  +, and sf  +
Gene taxonomy DNA-Binding: sequence-specific  +
Homolog cluster 108,655  +
Protein family 1.2 Winged Helix-Turn-Helix/102 Forkhead Domain Family  +
Protein group 1.2 Winged Helix-Turn-Helix   +
Personal tools