Foxp4 74123

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Gene ID: 74123
Gene symbol: foxp4
Gene Description: forkhead box p4
Aliases: 1200010K03Rik; 2310007G05Rik; mFKHLA
Human Ortholog Gene ID: [116113]
Reviewer Judgement: TF Gene
Functional Classification: DNA-Binding: sequence-specific
DBD Protein Group Classification: Winged Helix-Turn-Helix
DBD Protein Group/Family Classification: Winged Helix-Turn-Helix / Forkhead Domain Family
Homolog Cluster(s): 108655

Evidence:

Pubmed ID Function Species Evidence Strength Reviewer's Comments Reviewer
[14701752] DNA Binding Mouse Medium EMSA using in vitro translated proteins indicates Foxp4 binds specifically to the consensus forkhead site in the CC10 promoter. Amy Ticoll
Additional Reviewer Comments:
Reviewer: Amy Ticoll

EMSA using in vitro translated proteins indicates Foxp4 binds specifically to the consensus forkhead site in the CC10 promoter. Upon cotransfection with Foxp4 plasmids, activity of the mouse CC10 promoter is significantly repressed.


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Facts about Foxp4 74123RDF feed
Gene description forkhead box p4  +
Gene id 74,123  +
Gene judgment TF Gene  +
Gene symbol foxp4  +, 1200010K03Rik  +, 2310007G05Rik  +, and mFKHLA  +
Gene taxonomy DNA-Binding: sequence-specific  +
Homolog cluster 108,655  +
Protein family 1.2 Winged Helix-Turn-Helix/102 Forkhead Domain Family  +
Protein group 1.2 Winged Helix-Turn-Helix   +
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