Gadd45a 13197

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Gene ID: 13197
Gene symbol: gadd45a
Gene Description: growth arrest and dna-damage-inducible 45 alpha
Aliases: AA545191; Ddit1; GADD45
Human Ortholog Gene ID: [1647]
Reviewer Judgement: TF Gene
Functional Classification: Transcription Factor Binding: tf co-factor binding
Homolog Cluster(s): 13197

Evidence:

Pubmed ID Function Species Evidence Strength Reviewer's Comments Reviewer
[10872826] TF PPI Human Medium Yeast two-hybrid studies and GST pulldown assays indicate Gadd45a binds nuclear hormone receptors including RXR-alpha and RAR-alpha. Experiments were conducted with appropriate controls. Amy Ticoll
Additional Reviewer Comments:
Reviewer: Amy Ticoll

Yeast two-hybrid studies and GST pulldown assays indicate Gadd45a binds nuclear hormone receptors including RXR-alpha and RAR-alpha. Co-transfection assays in NIH/3T3 cells indicate Gadd45 proteins activate the transactivation function of nuclear receptors.


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Facts about Gadd45a 13197RDF feed
Gene description growth arrest and dna-damage-inducible 45 alpha  +
Gene id 13,197  +
Gene judgment TF Gene  +
Gene symbol gadd45a  +, AA545191  +, Ddit1  +, and GADD45  +
Gene taxonomy Transcription Factor Binding: tf co-factor binding  +
Homolog cluster 13,197  +
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