Klf5 12224

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Gene ID: 12224
Gene symbol: klf5
Gene Description: kruppel-like factor 5
Aliases: 4930520J07Rik; Bteb2; CKLF; IKLF
Human Ortholog Gene ID: [688]
Reviewer Judgement: TF Gene
Functional Classification: DNA-Binding: sequence-specific
DBD Protein Group Classification: Zinc-coordinating Group
DBD Protein Group/Family Classification: Zinc-coordinating Group / BetaBetaAlpha-zinc finger Family
Homolog Cluster(s): 107586


Pubmed ID Function Species Evidence Strength Reviewer's Comments Reviewer
[16595680] DNA Binding Human Strong KLF5 is shown to bind the GT boxes of the survivin promoter in CHIP and EMSA assays with EU-4 cells. Experiments conducted with appropriate controls. Amy Ticoll
Additional Reviewer Comments:
Reviewer: Amy Ticoll

KLF5 is shown to bind the GT boxes of the survivin promoter in CHIP and EMSA assays. Transfection of KLF5 into a KLF5-negative cell line EU-8 enhances survivin expression.

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Facts about Klf5 12224RDF feed
Gene description kruppel-like factor 5  +
Gene id 12,224  +
Gene judgment TF Gene  +
Gene symbol klf5  +, 4930520J07Rik  +, Bteb2  +, CKLF  +, and IKLF  +
Gene taxonomy DNA-Binding: sequence-specific  +
Homolog cluster 107,586  +
Protein family 2.1 Zinc-coordinating Group/17 BetaBetaAlpha-zinc finger Family  +
Protein group 2.1 Zinc-coordinating Group   +
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