Atoh1 11921

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Gene ID: 11921
Gene symbol: atoh1
Gene Description: atonal homolog 1 (drosophila)
Aliases: Hath1; MATH-1; Math1
Human Ortholog Gene ID: [474]
Reviewer Judgement: TF Gene
Functional Classification: DNA-Binding: sequence-specific
DBD Protein Group Classification: Zipper-Type Group
DBD Protein Group/Family Classification: Zipper-Type Group / Helix-Loop-Helix Family
Homolog Cluster(s): 11921

Evidence:

Pubmed ID Function Species Evidence Strength Reviewer's Comments Reviewer
[14757642] Co-activation Mouse Medium MATH1/E47 heterodimers bind an E-box-containing sequence flanking Hes5 in EMSA. Amy Ticoll
Additional Reviewer Comments:
Reviewer: Amy Ticoll

MATH1/E47 heterodimers bind an E-box-containing sequence flanking Hes5 in EMSA. Math1 regulates the expression of Notch receptors, ligands and the Hes5 effector in RT-PCR analysis.


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Facts about Atoh1 11921RDF feed
Gene description atonal homolog 1 (drosophila)  +
Gene id 11,921  +
Gene judgment TF Gene  +
Gene symbol atoh1  +, Hath1  +, MATH-1  +, and Math1  +
Gene taxonomy DNA-Binding: sequence-specific  +
Homolog cluster 11,921  +
Protein family 3 Zipper-Type Group/22 Helix-Loop-Helix Family  +
Protein group 3 Zipper-Type Group   +
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