Myod1 17927

From TFCatWiki

Jump to: navigation, search

External Links

Gene ID: 17927
Gene symbol: myod1
Gene Description: myogenic differentiation 1
Aliases: AI503393; MYF3; MyoD; Myod-1
Human Ortholog Gene ID: [4654]
Reviewer Judgement: TF Gene
Functional Classification: DNA-Binding: sequence-specific
DBD Protein Group Classification: Zipper-Type Group
DBD Protein Group/Family Classification: Zipper-Type Group / Helix-Loop-Helix Family
Homolog Cluster(s): 11921

Evidence:

Pubmed ID Function Species Evidence Strength Reviewer's Comments Reviewer
[12242286] DNA Binding Mouse Strong Gel mobility shift assays indicate murine MyoD binds specific sites in the myostatin gene upstream region. Experiments performed with expressed and purified MyoD, as well as C2C12 nuclear extracts. Results confirmed with ChIP assays in C2C12 cells. Amy Ticoll
Additional Reviewer Comments:
Reviewer: Amy Ticoll

Gel shift assays and ChIP assays indicate MyoD binds specific sites in the myostatin gene upstream region. Cotransfection experiments indicate MyoD preferentially up-regulates myostatin promoter activity.


DISCUSSION PAGE link for this gene

VIEW gene annotation feedback in the [TFCat Annotation Feedback Reports Inquiry]

REPORT gene annotation feedback on the [TFCat Annotation Feedback Reporting System] Help is available here


The section below defines information for semantic searching. Please see the help page for more information on this section.

Facts about Myod1 17927RDF feed
Gene description myogenic differentiation 1  +
Gene id 17,927  +
Gene judgment TF Gene  +
Gene symbol myod1  +, AI503393  +, MYF3  +, MyoD  +, and Myod-1  +
Gene taxonomy DNA-Binding: sequence-specific  +
Homolog cluster 11,921  +
Protein family 3 Zipper-Type Group/22 Helix-Loop-Helix Family  +
Protein group 3 Zipper-Type Group   +
Personal tools