Npas1 18142

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Gene ID: 18142
Gene symbol: npas1
Gene Description: neuronal pas domain protein 1
Aliases: MOP5
Human Ortholog Gene ID: [4861]
Reviewer Judgement: TF Gene
Functional Classification: DNA-Binding: non-sequence-specific
DBD Protein Group Classification: Zipper-Type Group
DBD Protein Group/Family Classification: Zipper-Type Group / Helix-Loop-Helix Family
Homolog Cluster(s): 11622

Evidence:

Pubmed ID Function Species Evidence Strength Reviewer's Comments Reviewer
[15635607] Non-specific DNA Mouse Medium ChIP assay on P0 mouse brain indicates NPAS1 Binds to the enhancer region of Epo. Amy Ticoll
Additional Reviewer Comments:
Reviewer: Amy Ticoll

ChIP assay indicates NPAS1 Binds to the enhancer region of Epo. Luciferase reporter assays in transfected HEK293 cells shows NPAS1 downregulates EPO expression.


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Facts about Npas1 18142RDF feed
Gene description neuronal pas domain protein 1  +
Gene id 18,142  +
Gene judgment TF Gene  +
Gene symbol npas1  +, and MOP5  +
Gene taxonomy DNA-Binding: non-sequence-specific  +
Homolog cluster 11,622  +
Protein family 3 Zipper-Type Group/22 Helix-Loop-Helix Family  +
Protein group 3 Zipper-Type Group   +
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