Nr2f1 13865

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Gene ID: 13865
Gene symbol: nr2f1
Gene Description: nuclear receptor subfamily 2, group f, member 1
Aliases: COUP-TF1; COUP-TFI; COUPTFA; EAR3; Erbal3; MGC118474; SVP44; Tcfcoup1
Human Ortholog Gene ID: [7025]
Reviewer Judgement: TF Gene
Functional Classification: DNA-Binding: sequence-specific
DBD Protein Group Classification: Zinc-coordinating Group
DBD Protein Group/Family Classification: Zinc-coordinating Group / Hormone-nuclear Receptor Family
Homolog Cluster(s): 110784

Evidence:

Pubmed ID Function Species Evidence Strength Reviewer's Comments Reviewer
[2739739] DNA Binding Human Strong Gel shift and methylation interference assays indicate COUP-TF binds to a specific region of the ovalbumin promoter. COUP-TF isolated from HeLa cells. Amy Ticoll
[17009409] Transactivation Human Medium Luciferase assays in HepG2[23] cells indicate COUP-TF1 regulates expression of HBV enhancer II. Amy Ticoll
Additional Reviewer Comments:
Reviewer: Amy Ticoll

Gel shift and methylation interference assays indicate COUP-TF binds to a specific region of the ovalbumin promoter. Luciferase assays indicate COUP-TF1 regulates expression of HBV enhancer II.


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Facts about Nr2f1 13865RDF feed
Gene description nuclear receptor subfamily 2, group f, member 1  +
Gene id 13,865  +
Gene judgment TF Gene  +
Gene symbol nr2f1  +, COUP-TF1  +, COUP-TFI  +, COUPTFA  +, EAR3  +, Erbal3  +, MGC118474  +, SVP44  +, and Tcfcoup1  +
Gene taxonomy DNA-Binding: sequence-specific  +
Homolog cluster 110,784  +
Protein family 2.1 Zinc-coordinating Group/18 Hormone-nuclear Receptor Family  +
Protein group 2.1 Zinc-coordinating Group   +
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