Ppard 19015

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Gene ID: 19015
Gene symbol: ppard
Gene Description: peroxisome proliferator activator receptor delta
Aliases: Nr1c2; NUC-1; NUC1; PPAR-beta; PPAR-delta; Pparb; Pparb/d; PPARdelta; [[gene_symbol:=PPAR[b]|PPAR[b]]]
Human Ortholog Gene ID: [5467]
Reviewer Judgement: TF Gene
Functional Classification: DNA-Binding: sequence-specific
DBD Protein Group Classification: Zinc-coordinating Group
DBD Protein Group/Family Classification: Zinc-coordinating Group / Hormone-nuclear Receptor Family
Homolog Cluster(s): 110784


Pubmed ID Function Species Evidence Strength Reviewer's Comments Reviewer
[11923467] Other Human Strong Demonstrates nuclear localization. Jared Roach
Additional Reviewer Comments:
Reviewer: Jared Roach

Nuclear hormone receptor. I could not find a reference that clearly and unambigously demonstrates DNA binding. However, I know of no nuclear hormone receptor that is not a TF. So this raises my evaluation just beyond the "candidate" bar.

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Facts about Ppard 19015RDF feed
Gene description peroxisome proliferator activator receptor delta  +
Gene id 19,015  +
Gene judgment TF Gene  +
Gene symbol ppard  +, Nr1c2  +, NUC-1  +, NUC1  +, PPAR-beta  +, PPAR-delta  +, Pparb  +, Pparb/d  +, and PPARdelta  +
Gene taxonomy DNA-Binding: sequence-specific  +
Homolog cluster 110,784  +
Protein family 2.1 Zinc-coordinating Group/18 Hormone-nuclear Receptor Family  +
Protein group 2.1 Zinc-coordinating Group   +
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