Pparg 19016

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Gene ID: 19016
Gene symbol: pparg
Gene Description: peroxisome proliferator activated receptor gamma
Aliases: Nr1c3; PPAR-gamma; PPAR-gamma2; PPARgamma
Human Ortholog Gene ID: [5468]
Reviewer Judgement: TF Gene
Functional Classification: DNA-Binding: sequence-specific
DBD Protein Group Classification: Zinc-coordinating Group
DBD Protein Group/Family Classification: Zinc-coordinating Group / Hormone-nuclear Receptor Family
Homolog Cluster(s): 110784


Pubmed ID Function Species Evidence Strength Reviewer's Comments Reviewer
[14744933] Transactivation Rat Medium Transactivation : PPAR-gamma bound promoter - CAT reporter gene construct. PPAR-gamma associated with RXRα transactivates the UCP-1 promoter very poorly in fibroblasts, but a powerful transactivation is observed when adding PGC-1 (PCG1 alone can not transactivate the reporter gene). David Martin
[15681609] DNA Binding Unknown Strong DNA binding is determined by DNA mobility-shift assay and chromatin immuno-precipitation (ChIP). David Martin
Additional Reviewer Comments:

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Facts about Pparg 19016RDF feed
Gene description peroxisome proliferator activated receptor gamma  +
Gene id 19,016  +
Gene judgment TF Gene  +
Gene symbol pparg  +, Nr1c3  +, PPAR-gamma  +, PPAR-gamma2  +, and PPARgamma  +
Gene taxonomy DNA-Binding: sequence-specific  +
Homolog cluster 110,784  +
Protein family 2.1 Zinc-coordinating Group/18 Hormone-nuclear Receptor Family  +
Protein group 2.1 Zinc-coordinating Group   +
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