Prdm1 12142

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Gene ID: 12142
Gene symbol: prdm1
Gene Description: pr domain containing 1, with znf domain
Aliases: Blimp-1; Blimp1; PRDI-BF1; ZNFPR1A1
Human Ortholog Gene ID: [639]
Reviewer Judgement: TF Gene
Functional Classification: DNA-Binding: sequence-specific
DBD Protein Group Classification: Zinc-coordinating Group
DBD Protein Group/Family Classification: Zinc-coordinating Group / BetaBetaAlpha-zinc finger Family
Homolog Cluster(s): 107586

Evidence:

Pubmed ID Function Species Evidence Strength Reviewer's Comments Reviewer
[1851123] DNA Binding Human Medium EMSA indicates PRDI-BF1 binds specifically to the PRDI element of the beta-IFN gene promoter. Amy Ticoll
Additional Reviewer Comments:
Reviewer: Amy Ticoll

EMSA indicates PRDI-BF1 binds specifically to the PRDI element of the beta-IFN gene promoter. Cotransfection experiments in cultured mammalian cells reveals PRDI-BF1 is a potent repressor of PRDI-dependent transcription.


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Facts about Prdm1 12142RDF feed
Gene description pr domain containing 1, with znf domain  +
Gene id 12,142  +
Gene judgment TF Gene  +
Gene symbol prdm1  +, Blimp-1  +, Blimp1  +, PRDI-BF1  +, and ZNFPR1A1  +
Gene taxonomy DNA-Binding: sequence-specific  +
Homolog cluster 107,586  +
Protein family 2.1 Zinc-coordinating Group/17 BetaBetaAlpha-zinc finger Family  +
Protein group 2.1 Zinc-coordinating Group   +
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