Rara 19401

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Gene ID: 19401
Gene symbol: rara
Gene Description: retinoic acid receptor, alpha
Aliases: Nr1b1; RAR; RARalpha1
Human Ortholog Gene ID: [5914]
Reviewer Judgement: TF Gene
Functional Classification: DNA-Binding: sequence-specific
DBD Protein Group Classification: Zinc-coordinating Group
DBD Protein Group/Family Classification: Zinc-coordinating Group / Hormone-nuclear Receptor Family
Homolog Cluster(s): 110784

Evidence:

Pubmed ID Function Species Evidence Strength Reviewer's Comments Reviewer
[1312934] DNA Binding Other Strong "The human retinoic acid receptor alpha was expressed in Escherichia coli for ligand and DNA binding studies. The recombinant receptor showed the expected DNA binding activities in gel-retardation assays. The dissociation constant for highly specific bound retinoic acid was found to be 0.67 nM. The affinity of several synthetic retinoids to the recombinant protein was determined and compared to their biological activity." Jared Roach
Additional Reviewer Comments:
Reviewer: Jared Roach

Well-known hormone receptor.


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Facts about Rara 19401RDF feed
Gene description retinoic acid receptor, alpha  +
Gene id 19,401  +
Gene judgment TF Gene  +
Gene symbol rara  +, Nr1b1  +, RAR  +, and RARalpha1  +
Gene taxonomy DNA-Binding: sequence-specific  +
Homolog cluster 110,784  +
Protein family 2.1 Zinc-coordinating Group/18 Hormone-nuclear Receptor Family  +
Protein group 2.1 Zinc-coordinating Group   +
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