Runx2 12393

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Gene ID: 12393
Gene symbol: runx2
Gene Description: runt related transcription factor 2
Aliases: AML3; Cbf; Cbfa-1; Cbfa1; LS3; Osf2; Pebp2a1; PEBP2aA; Pebpa2a
Human Ortholog Gene ID: [860]
Reviewer Judgement: TF Gene
Functional Classification: DNA-Binding: sequence-specific
DBD Protein Group Classification: Other
DBD Protein Group/Family Classification: Other / Runt Domain Family
Homolog Cluster(s): 12393

Evidence:

Pubmed ID Function Species Evidence Strength Reviewer's Comments Reviewer
[11451945] DNA Binding Mouse Medium EMSA shows that anti-Cbfa1 antiserum binds to the ameloblastin promoter. Sarav Sundararajan
[16574347] DNA Binding; Transactivation Mouse Strong Luciferase reporter assays using the musinr Osterix (osx) promoter show that Runx2 can transactivate expression, while gel shift experiments show that Runx2 specifically binds to the osx promoter. Sarav Sundararajan
Additional Reviewer Comments:


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Facts about Runx2 12393RDF feed
Gene description runt related transcription factor 2  +
Gene id 12,393  +
Gene judgment TF Gene  +
Gene symbol runx2  +, AML3  +, Cbf  +, Cbfa-1  +, Cbfa1  +, LS3  +, Osf2  +, Pebp2a1  +, PEBP2aA  +, and Pebpa2a  +
Gene taxonomy DNA-Binding: sequence-specific  +
Homolog cluster 12,393  +
Protein family 7 Other/110 Runt Domain Family  +
Protein group 7 Other   +
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