Tgif2lx 245583

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Gene ID: 245583
Gene symbol: tgif2lx
Gene Description: tgfb-induced factor homeobox 2-like, x-linked
Aliases: MGC130458; Tex1
Human Ortholog Gene ID: [90316]
Reviewer Judgement: TF Gene
Functional Classification: DNA-Binding: sequence-specific
DBD Protein Group Classification: Helix-Turn-Helix Group
DBD Protein Group/Family Classification: Helix-Turn-Helix Group / No Family Level Classification
Homolog Cluster(s): 103889

Evidence:

Pubmed ID Function Species Evidence Strength Reviewer's Comments Reviewer
[8537382] DNA Binding; Transactivation Human Strong EMSA assays show that TGIF homeodomain interacts specifically with the retinoid-responsive element CRBPII-RXRE and that the binding of this site by TGIF and RXRa is mutually exclusive. CAT reporter assays using the CRBPII promoter show that TGIF can repress both basal and RXRa dependent transactivation. Sarav Sundararajan
Additional Reviewer Comments:


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Facts about Tgif2lx 245583RDF feed
Gene description tgfb-induced factor homeobox 2-like, x-linked  +
Gene id 245,583  +
Gene judgment TF Gene  +
Gene symbol tgif2lx  +, MGC130458  +, and Tex1  +
Gene taxonomy DNA-Binding: sequence-specific  +
Homolog cluster 103,889  +
Protein family 1.1 Helix-Turn-Helix Group/999 No Family Level Classification  +
Protein group 1.1 Helix-Turn-Helix Group   +
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